The problem with a Macclesfield to Buxton service would be that using the Buxton line the only direction you can go from Buxton is towards Stockport, which you can already do from Macclesfield. This would probably mean that there wouldn't be all that many people using the train between Macclesfield and Buxton at off-peak times unless a further line was built going in to Buxton.
With regards to additional trains between Runcorn and Liverpool, Virgin Trains would probably oppose it as they want to increase the number of Liverpool to London trains, not that they should always get their own way!
With regard to other services that haven't happened:
A local paper reported a few years ago that there was once plans to build a Macclesfield to Warrington service which would have called at Knutsford. I can't remember which station in Warrington it was planned to go into, but whichever station it was it could have cut journey times from the eastern side of Cheshire to Warrington and Liverpool and if it was Bank Quay station then also Bolton and Preston.
Cheshire County Council also stated quite a while ago that the Altrincham to Stockport line should be joined to the Manchester to Manchester Airport which is crosses, which is logical as the only trains which arrive at Manchester Airport without first calling at Manchester Piccadilly are local trains from Crewe or Alderley Edge.
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